I've also thought about the Winchester PDX1 line as well. I don't believe any sort of barrier penetration (before hitting the target) would be a concern. It's hard to imagine too many justifiable home defense uses for going through a barrier before. Otherwise, I would probably use something like a NATO Green Tip if I was going for barrier penetration.

The concern with the Federal and some others I've seen (that are soft point) are the warnings/notices/etc that always say "ONLY CHAMBER ONCE". I'm assuming it's due to the fact that they are soft tip, and if that happens to get butchered/flattened/otherwise-non-pointed that it could hang on the feed ramps before being chambered properly. The 75gr Hornady looked quite smooth but the 55gr version did not look so smooth as to not have that issue. Obviously if the 75gr won't hit the target out to 25-50-100 yards, that's a much bigger problem than not feeding at all!