I would shoot it first to see if it's accurate to the POA. If it's accurate I'd leave it alone. If it bothers you that much then send it back for repair.

Aren't the screw in barrels hand fitted till they lock in place tight?

I picked up a new unshot s&w m29-10 6 1/2" with all the accessories and the presentation case for $699. The PO purchased it and traded it in. It has a hairline of light under the extractor housing at the bottom. The barrel is perfectly aligned. She's a keeper.

My other three new s&w look perfect barrel alignment wise.

I'm still staying with s&w n frames in nickel of course. But I also want a ruger in 357mag. too in stainless unless I can hold the s&w first to see how it feels(686).