I too use my Dillon exclusively for handgun ammo, loading my rifle stuff on an RCBS Rockchucker.

I love the Dillon except for when I have to change the priming system from one size to another. Another potential drawback is: the press would be safer to use of the shell plate automatically rotated as the lever or arm was returning to the upright position, thus further guarding against an accidental double charge, which can happen if you become pre-occupied with a problem at the first station.

As with any reloading system, procedure or product,
avoid distractions and only load when you're mentally fresh and sober. There's only so much idiot-proofing that can be built into a reloading press.