I will add to what Bob says by saying that he is correct. As you are perhaps a new shooter, or one unfamiliar with autos, when Bob mentioned "set-back" he is talking about a bullet seated too deeply in the chamber. This can happen to high quality ammo and is often the result of chambering a round over and over. It can happen in some cases as quickly as three or four chamberings and in others a few more. While it looks neat in the movies to see the good guy loading up every morning before work, it is actually a dangerous practice to repeatedly chamber, eject and re-chamber the same round. Fortunately, you can check for "set-back" by lining up all of the cartridges on a flat surface. Lay a straight edge across the top and safely discard any that are shorter than the rest. Or, you can get a micrometer and measure each round, but that is a drag.

As to the proper condition of your pistol, I suggest that your carry pistol be left loaded and that it be stored in a locking gun box such as Gunvault or similar so that you do not have to re-chamber every time you want to carry. This is, of course, likely to give all sorts of heartburn to people who are concerned about such matters as it is contrary to the way in which ALL firearms that are NOT maintained for instant readiness should be stored. All firearms not maintained for instant readiness should be stored in a locked area or safe, unloaded, with ammo in its original packaging locked in a separate safe or cabinet.