Shortly after I started handloading in 1980 I started looking for a good load in the 41 Magnum. Ken Waters' Pet Loads book stated his best load for the middle magnum was 21 grains of IMR 4227 behind a 210-220 grain cast bullet, if memory serves. I used that load behind the Lyman 410459 for a lot of years; it was always more accurate than I was, and Ken's statement that recoil seemed softer than with other powders was exactly my experience as well...