A .32 Airweight Centennial woul be sweet.
The.32 is a LOT easier to shoot than the .38, especially in an Airweight.

I tend to believe Buffalo Bore's claims.
Their rounds are chronied through real guns, and there have been several ballistic gelatin tests of their ammo that seem to bear out their claims.

Either .32 or .38 will make a clean, free-bleeding hole with the hard-cast wadcutter ammo,
Either one is worlds better than an unexpanded HP or a round nosed projectile.
Given my druthers, I'druther have a .44 Special or .45 Colt wadcutter load for SD.
However, those are generally bigger, heavier guns that aren't as easy to conceal in hot weather.
Even the Charter Bulldog .44 is bigger than a J frame.
No heavier than a steel frame J, but still bigger, especially with grips that make it comfortable to shoot.

The Taurus Judge and Smith Governator are bigger/heavier still.
The most practical use for either is as a snake gun (IMO), with .410 birdshot, which is the reason I got the Judge. As a gun for large pit vipers, it and the Governator have no peer.
As SD guns, they'll work fine, but I don't see a real advantage.

So, a lightweight, laser-accurate gun that is easy to shoot and creates a clean, free-bleeding hole through a bad guy definitely has merit.
Maybe not as good as a .44 or .45, but worlds better than any unexpanded HP.

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What would Jim Cirillo do?