As others have said, take a look at the BMW boxers. My old R90S weighs about 450 pounds. When I was riding a lot I could put it back upright if something happened that it tipped over. I am not sure BMW still takes the weight issue as serious as they used to, but I'd bet they are lighter than similar displacement Japanese brands.
I am not far from your age and also thinking about a new or new-to-me road bike. The kids are in college now and I have some time to do that sort of thing. I think I have "given up riding" long enough.
I like a bike that I feel I can control, not a bike that overpowers and controls me. When they get too heavy, too uncomfortable, or even too powerful, I lose interest. (I don't need a 180+ MPH street bike.) I'll be having a look at the new and not-so-new Beemers, probably this winter some time.