Sadly last year a police officer in my area died from a single hit with a 25. Hit his carotid in the neck. If it is what you have it can do the job. Every caliber has stories of spectacular stops and failures attached to it. There seems to be a tendency to amplify small caliber failure and dismiss large caliber failures. I shoot and carry a beretta 21 in 25 acp from time to time. I actually shoot it and rapid fire mag dumps at 7-10 yards are held inside a playing card and at 25 yards can hold groups inside the ten ring of a ppc target. Shot placement is king. Hit the right spot regardless of caliber it will work wrong spot same thing for failures. There are lots of stories of 45's hitting people multiple times and not stopping them. Today there are better hideout guns and calibers for sure. But a well placed 25 can ruin an assailants day no doubt