I have one in 4" and another in 6" and have shot both extensively.
The 25-9 model is when they finally got all of the details put together properly (cylinder throat and barrel/forcing cone dimensions, action etc.) and these are the two most accurate 45 LC's that I own. Penn Bullets offers a 225g full wadcutter that sits deeper in this oversized case and makes excess powder space a non-issue. If I would quote group sizes, you would probably call me a liar, but, suffice it to say, they will match anything I can wring out of my highly accurate 44 Specials.