In the case of the 9mm ammo, I have had the 115gr GD HP at;
1227-1288...... 61fps
1189-1208......19fps
1120-1165......45fps
#1 45fps in the last load can cause the bullet to not open up, if the low fps happens.
#2 some bullets have a harder copper jacket which can cause over penetration.
3. In HP bullets, in a 4G test, the tip can clog, causing over penetration/

#4 these test are in Gel, not a human body with skin and bones.
Gel is nice to see what happens but it is a different world on the real thing.
If your round has to penetrate an out stretched hand (palm)
and then a forearm before even getting to the body, is over penetration bad ?

Later.