What I've learned from this thread:

#1 The least effective caliber pocket gun for you...depends on the size of your pockets

#2 With a .380, I can shoot a skinny man wearing a T shirt, but not a fat guy on drugs in a leather jacket.

#3 "...the more bullet wounds a patient had the more likely the patient was going to die..."

#4 I'm better off with a sharp stick than a .32

But seriously...

One problem with these little pocket guns is, they become increasingly difficult to shoot acurately the smaller they get. Keeping my Kel Tec P32 in the black at 7 yds is not easy, I can't imagine shooting it accurately under duress. But that is my summer carry; either in my cargo shorts pocket, or clipped inside the waistband of my athletic shorts.