What are the characteristics of that gun you don't want locked up in an evidence locker or possibly gone forever?
An expensive, well made, ergonomic, reliable and accurate gun that would be hard to replace?
Why is that? Because they are in high demand? Because of those attributes?
Aren't they the same descriptors of a gun you would bet your life on?
Isn't the fact that they are probably the best choice for self defense also the reason they are expensive and prized?
I would probably favor a family heirloom a little more, but then mine are all hunting guns and not carry pieces.
This is not to say that only expensive, hard to replace guns are best for defense. There are plenty of inexpensive, easily replaced choices these days that work very well.
But, if I trust and shoot my favorite pristine 2" model 19 or whatever, better than any other....that's what I will carry and rely on.
I can't take it with me.