"4227 used to be a very popular powder for the 22 Hornet when I was growing up. Don't know what is used now, there's so many different choices and not so many Hornet shooters anymore."

Too true. Many years ago I had a Win Model 43 in .22 Hornet (my very first CF rifle), used it for crow hunting. But I didn't reload when I owned the M43. Many today have never heard of it, but the .22 Hornet is the perfect cartridge for smaller game and varmints out to around 150 yards and it doesn't make much noise. It was very popular in the 1940s and 1950s. I even had a friend who successfully used a similar rifle in .22 Hornet for deer (which was legal in Maryland at that time). It deserves to make a comeback, but I don't believe that's possible.