I kind of stopped worrying about this in the context of accuracy. My Dillon powder measure doesnt seem to throw Unique very consistantly. At the range those Unique .44 loads sounded like bang, pop, boom...but they all went in the same place at ten yards.

Where I do get concerned is inconsistant drops with very fast powders. The easy answer is to stay away from the top of the load range, I suppose. This is how I approach Clays, and it has been very good to me as a bullseye propellant.