The most important consideration is where YOU can put the bullet. Assuming sufficient penetration to reach & damage vital systems and/or structures of the body, energy, velocity, diameter or other ammunition parameters are meaningless.

FWIW, the 165 gr bullet was developed to eliminate what some felt was a excessively steep pressure/time peak with the 180 gr bullet. Try both for shot placement under time pressure and see which you do better which or if there is any significant difference at all.