Guys there are no "hard and fast rules" no 'guaranteed one shot stops".....if there were rules; in the real world there are exceptions........and if a round/gun combo guaranteed one shot stops....... we'd all be carrying it!!!!!!!!!!
So we all just need to decide what works best for us ........ size,shape caliber and capacity.......... accept the inevitable short falls; then ..... hope for the best but plan for the worst!!!!!!!!