This argument about not using Ruger only loads in 25-5's because they supposedly can not handle the pressure comes up every so often. The 45 Colt SAAMI pressure is 14000 psi. The 25-2's in 45 ACP handle the 45 ACP +P rounds at 21000 psi. Many 25-2s have been converted to use 45 Super rounds which are 28000 psi. Also to consider are the many Model 25's converted to handle the 460 Rowland which generates 40,000 psi.

Constantly using heavy loads will take it's toll on any weapon. Some will show signs of wear sooner than others. The Ruger tier 2 loads I would think using 45 Colt loads in the 20000 - 27000 psi range every so often wouldn't be a problem in a 25-5.