And this pretty much sums it up for me! You take the time to get to know your weapon inside and out; you maintain and train with it and use quality ammo. If I had to estimate how many rounds I've slung down range since I've been shooting... I started at 20year old and I'm 40 now... I'd comfortably say I've pulled a trigger 50 to 60 thousand times in various platforms... 1911's, Glocks, M&P's, CZ's, Smith & Colt revolvers of various calibers. In all that time and rounds shot I can count also comfortably say I've experienced maybe a couple dozen failures. That is a hell of a track record if you ask me. And half of those failures were due to quality branded factory ammo that simply had a round or two out of spec, i.e. a case length that was a half a millimeter too long, a primer that popped it's pocket, the bullet's OAL too long/short, etc... The other's I remember were worn/over stressed and fatigued magazine springs... 1911's, albeit my absolute favorite semi-auto's suffer the most from spring fatigue in my experience. I put my revo's and semi-auto's to be on par in reliability and bet my life on them almost every day. I work in Real Estate and my downtown Atlanta office is two blocks away from the CNN Center... not a very savory side of the city. Common sense and putting 300-400 trouble free rounds down the pipe of a semi-auto before CCW-ing it is a must. 200 of the same with any quality revo is a must too. YMMV...

ETA: The above round count and failure count excludes any and all .22Rimfire cartridges of course... I was strictly talking about centerfire cartridges!