I have a 500 and I like it. When I decided to go ahead and get an X frame I was planning on a 460. I am a 45 colt fan, already cast bullets in that caliber and have a fair stock of jacketed. Liked the idea of being able to fire my 45 colt loads in the 460. But, then came a great deal on a 500, complete with Leopold scope, so I took the deal and am happy. I have my hand cannon. I believe it would be hard to show that one of the 2 is really that much better at anything than the other. If you have a 44 mag, 41 mag, 45 colt or even a 44 special, whats the real point of being able to fire anything but, the real thing in either? They are very bulky and heavy, and "versatile" is not a word I would apply to either no mater what they can fire. Someday I may pick up a 460, maybe a 4-6", but no real hurry or need. Ya, need. LOL If I had guns based on any kind of need at all. I wouldn't have anywhere near so many.