Look for Dr. Roberts's testing, pick a few of the recommended loads that might appeal to you, buy 50 rounds and see how they feel to shoot, etc. Once you think you have one you find workable for you, buy 1000 rounds or more, function test the pistol with 300-500 rounds, and as long as it works reliably every time (a pistol should not need cleaning, and probably not lube if you are using quality lube) during that period, load up, and drive on.

This is the same as with any other defensive pistol. The only difference the caliber makes is where you look on Gary's test results.

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NHI, 10-8.