586/686 wins hands down. I have a python that I got new from the Colt custom shop in 1980. With moderate shooting it has went out of time twice. Both times I had to PEEN the hand to stretch it to get it back in time.
Where as I've never had any of my Smiths go out of time. For my use ANY Smith revolver is better for daily use than a python. 99.9 percent of today's python owners that wax eloquently about their pythons never tote or shoot them. They just lie in someone's safe to be bragged about. Truthfully they are really worth 30-40% of what they sell for now.

And shame on S&W that hired the full lug guy who put full lugs on everything including the water hose nozzle.

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S&W Accumulator