Bill got it right, the 4006 platform is not capable of handling the length of the 10mm cartridge.

I would disagree about the chamber not being able to handle the 37,500 psi of the 10mm cartridge when it has already been shown that a 4006 sized chamber can handle the 40,000 psi 357 Sig.

Unfortunately, the 4006 chamber can not handle the length of the 10mm cartridge, so it is academic.

John