My EDC is a Glock 42. For my body geometry, it just "fits." And at the range, I'm a surgeon with it at 15 yards.

In truth, the M&P and Glock platforms are both excellent, tried-and-proven, and have undergone multiple iterations to work out the bugs. On paper there's not much to recommend one over the other, so at the end of the day I'd go with what you're most comfortable with.

Mike