No, I don't practice with my carry ammo.

If we're talking about a handgun for self-defense purposes, point-of-aim and point-of-impact differences are negligible.

Only reason to shoot carry ammo is to confirm they function in your gun, and if you're concerned that the ammo you have had is now 'so old it may not function'... which my guess would be, a time period greater than a couple decades. Maybe it's less if you bang and shake your carry piece a whole, whole lot, but even then, you're talking about swapping out a couple magazines' worth. And I don't consider occasionally shooting off your mags and reloading them with fresh, as practice.

The current climate has changed my patterns, but I would frequently shoot several hundred rounds at the range, getting and staying comfortably familiar with my handguns. I'm not doing that with Gold Dots, I do that with ball ammo. Cheap ball ammo. My only requirement with that was that it be consistent, and inexpensive.