I use A-2400 in my 38 Spl. brass with a 158 gr. LSWC, cast and Speer swaged hollow points. I do push them a bit and even us CCI Mag primers. (the older manuals said to do so and I'm not changing now). Years ago I chronographed my load out of a 2" S&W Model 10 and got 908 fps. I was mildly impressed. Mostly use them in my 357's but the Speer hollow points are my carry load for my 2" S&W Mod. 36. Amazingly accurate and velocity is there as well enabling the Speer hollow points to expand in my 36. Never had an issue with my loads so I never looked at other powders, though some day I'm going to work with Unique to see what that'll do.