Personally I wouldn't shoot a whole lot of 357 125s in the 19. I have 3 19s and a 66-1. I have shot a few Rem 125s through them all but the majority in factory ammo have been Rem 38s with the 125 gr+P HPs. Most of the 357s were fired from one of my N frames. 2 pre 27s 3 1/2 and 5 inch and one of the 3 27-2s 2- 5 inch one 3 1/2. I bought 2500 rounds of Rem 38 125 +P and 357s each some years ago. . Still have a few of each left. No problems with any guns. I also have a pre 15 Combat masterpiece that has had approx 2000 rounds of 38 125+P...no problems with it either. I like the Rem 125 HP bullets as they shoot well in my revolvers. I bought a 1000 to load my own