Nice revolver there Shark Bait!
ssig - I've got one of those old NYST Colt 45's as well. Have some reproduction grips on it and it shoots quite well.
Typically I'll load 250 - 255 gr bullets for it at 850 - 900 fps. I don't shoot it often, a box or two of handloads every year is all. Have had it about 40 years and it did belong to my grandfather. Good old guns. I really ought to get a nice belt holster for it. Might use it more if I had one.
Regards, Guy