Considering that many makers- Colt, S&W, Taurus and others have been making alloy frame revolvers for years, I highly doubt that regular shooting will wear it out.

I have a friend that has carried an old model 37 for so many years, that all the writing on the sides of the barrel is gone from it being in his pocket with change and keys and it looks like a "stainless" gun because there is no finish left on it, unless you call scratches and gouges finish.

Yes, the center pin from the cylinder will cut a trough in the frame where it traverses it, but this is only natural. A good polishing though to make certain there is no burrs on it won't hurt a thing.

I guarantee you that it will outlast most of all of us on this board if it is well maintained. Now, I didn't say the finish will take that much abuse, but the finish on a blued gun will come off after carrying it every day in a pocket for 20+ years too. (I've seen it!)

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Lost it all in a boat accident