I carry all my 1911s cocked and locked, they were designed that way, and for good reason.

As long as your comfortable with it and have a suitable holster go for it. There is also a safety check... With thumb safety engaged, pull trigger hard and release, hold the pistol to your ear, then pull the hammer back a little, if you hear a click, have a new safety fitted, if not your good to go. Also be sure your grip safety works as it should.

If these two things check out your ready for cocked and locked.