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Is that based upon actual tests you have done?
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I don't need to do tests to know if you use 8.5gr HS-6 under a 158gr bullet it will produce both more pressure and velocity than if you use 6.2gr HS-6 for the .38 Special or 6.6gr HS-6 for the .38 Special +P which is the Hodgdon Max recommended charges today. Those rounds were fired in the old Model 10's for decades with no ill effects.