No.I use them on small vermin around the house, snakes, mice, starlings,chipmunks,etc.I've had no problem with the shotshells in any of my revolvers. Remember that they are only lethal at short range no matter if they are fired from .22 or a centerfire. I have found that 15 to 20 FEET is about the maximum although the 44 or 45 just might get you a few more feet because of a larger shot charge. Unless a grouse is actually sitting on my front sight I don't think I would try to kill one with a shotshell from my revolver.Just my opinion.
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