I carried both my 627 and 657 PDRs when they first came out
I prefer the old Factory Combat grips in any of there variations over those Secret Service boot grips. I used the Factory holster which is made for them by Gene DeSantis
Then the 2" 327 came out. When I got mine in 2004 I switched to it as it could even be pocket carried in 5.11's Covert Khakis or other pants/jackets with BIG pockets. I like the Pachmayr Compacs on these guns
The 2" 327 weighs in at one ounce lighter than a Model 60 chambered for 38 Special.
Just 4 years later I got my 2 1/2" 327 Night Guard. It is a bit heavier than the 2" 327 but it has better sights and that extra weight helps mitigate recoil to some degree. The Night Guard is still small enough and light enough to fit in 5.11's Covert Khakis so I was thrilled at this new revolver
As to ammunition in any of these, Initially I was carrying the 158 grain Remingtons, but that is because I had come into 7+ cases of it. Once all of that was shot up I switched to the Hornady 140 grain XTP.
My third option is still a 125 grain JHP with the Remington SJHP as my favorite load of all time.
All of the ammunition I shoot is FULL POWER
I realize that Full Power ammunition is not for everybody and a 357 lite is still better than a 38 Special