Stop using Unique for handgun loads. In meters poorly which results in a charge variation of +/- 0.51 grain and it's primarily a SHOTGUN powder. BTW, shotgun loads position the powder right over the flash hole and the powder is retained in that position by the wad. So shotgun powders are designed without any consideration of Position Sensitivity. Something I discovered when I tried using SR7625 in a 38 special load. This resulted in loads that produced 400 fps if the barrel was held pointing straight down prior to firing and 700 fps if the barrel was held straight up prior to firing. Note the barrel was held horizontal when firing and brought to that position so that the powder charge was clustered either at the bullet base or near the flash hole.
I would suggest that you use an actual Handgun powder, such as Vihtavouri N340, N350 or 3N37. They feature a near zero position sensitivity, meter wonderfully, and are very clean burning.
BTW, if you have a stash of Unique you want to sell after discovering how good the Vihtavouri powders really are you will find that Shotgun reloaders will gladly pay 40 dollars a pound for your unopened bottles of Unique. It is a wonderful powder for 20 and 28 gauge loads and currently nearly impossible to find. Post a for sale notice at a local shotgun range and you'll get plenty of calls wanting to buy.