Stefano, you're right that, logically, the load depends on what you want to do. In my case, the difference in recoil between a 1200FPS load and a 1000 FPS is enough that I use the slower one almost exclusively. The fact that it is also much easier on the gun is definitely a plus, too. I think you're also quite right that these rounds penetrate way too much to be used anywhere except out in the field.
I just bought a new keg of Unique powder. Last Saturday, I was checking it to be sure there were no substantial changes compared to my old supply. I don't normally chronograph the long barrelled guns (8-3/8") because I use them so infrequently, but in this case I did. Here is the result:
Load: H&G #326 276 gr .430" dia., 9.0 grs Unique, Win LP primer, Federal case.
4" barrel, 1015 FPS average, 30 FPS extreme spread, 12 FPS standard deviation
5" barrel, 1006 ave, 28 es, 10 sd
6.5" barrel, 1024 ave, 7 es, 2 sd
8.375" barrel, 1081 ave, 19 es, 7 sd
This type of load represents the top end of what I actually enjoy shooting in a 44 Magnum revolver. Anything more than this is work, not pleasure.
The reason I do not favor 250 gr bullets for the 1000 FPS load is that I have always used Unique and do not get good consistency with the 250 gr bullet at that velocity. Extreme spreads run 70-80 FPS. A change to another powder might cure that - W231, maybe Universal... ? I don't know. I do know the 276 gr bullet cures the problem with Unique.
Naturally, the data shown is for reference only, and, like any other published data, should be used with all regular handloading precautions.