A modern Schofield isn't like the old versions....its cylinder is sized to accept the .45 "Long" Colt and so it should easily handle any standard pressure .45 Colt, especially considering such Factory loads are loaded extremely mildly, and "Cowboy Action Shooting" loads are loaded lighter still.
I have a Schofield that easily digests handloads of 255gr LRNFP sitting on top of *.*gr of Herco that I have personally chrono'd from one of my 5.5" barrel 1873's at 900 fps. It is I believe a much better approximation of the REAL black powder loads back when the Colt used balloon head cases that could accept a full 40 grain charge of black. I once put a lot of time and effort into trying to duplicate original loads using modern, clean-burning BP substitutes and it's fun to see that huge bullet pressed down onto an equally huge powder charge but the maximum charge I could squeeze into a modern solid head case was 35 grains and that was compressed (yes I am a maniac).
I also got tired of the corrosive effect that even BP substitutes have on brass (that's why nickel plated is wonderful), and switched over to "modern" powder.
I actually LIKE the loading volume of Herco in the big Colt case and it's easy to get a potent load that barely stresses a modern case.
I realize the original Schofield was designed around a U.S. Army standard 28 grain charge of black under a 230 grain slug (because the Army never actually used the commercial loading of 255gr/40gr, but a modern reproduction built from modern steel is a LOT stronger and should handle a decently powerful load.