Yes, you probably get more velocity with 2400, but at the cost of a massive increase in muzzle blast. Please also read the 3rd paragraph.
Decades ago, I settled on Unique for lighter loads and IMR 4227 for my full power loads. You do need to tap the case to settle the powder somewhat depending upon where the cannelure is on jacketed bullets (my loads are somewhat compressed) but I've never regretted any slight loss of velocity. No bullet ever bounced off any critter I shot with the loads. Never needed more than one shot.
FWIW, I did a couple of blind accuracy tests back when at 100 yards comparing my handloads (same bullet) and Remington factory 240 gr SJHP. The handload groups were half the size of the factory. I was and am willing to trade some velocity for the smaller group. I do use CCI magnum pistol primers.
BTW, the Remington 240 gr SJHP is a under appreciated bullet. I settled on that one eons ago. Plenty of penetraton, massive expansion on white tails.