Never had any experience with 'Clear Shot'.
Used 'Clean Shot' since it came on the scene several years ago. It has since changed name to 'American Pioneer'.
Same stuff and I continue to use it both in M/L and cartridge.
Not good in a F/Lock,,so the real BP is for that.
I've forever read and heard the reports of Clean SHot/American Pioneer spoiling in short term storage, clumping up, going bad in the factory sealed containers, etc.
I've never had that happen in all the years I've used it. I have never had any of it fail to work as it is supposed to. Yes it will lightly 'clump' in the container but it falls back apart when you pour it out and begin working with it. The older stuff will slightly change in color. I have a case of the older 'Clean SHot' brand from probably 10 years ago that I bought and put away after using 2 pounds out of the case and opening a third. That open canister was recently used with no problems in 44-40 reloads and the unopened bottles have their potency unaffected as well.
If any of that was dangerous, I'm sure it too would be gone from the market. If the clumping was in itself dangerous, I'd doubt the'd mfg it it in pellet form for preloaded charges.
Yes cleaning is as simple as the ads say. A patch or two with just plain water, then oil. No fouling at all in the action of repeaters.
But there is still nothing quite like the real thing in a M/Loader
Never used Pyrodex or 777 so I can't comment on those.