No smilies necessary, TX*; your observations on grips make more sense than most.
If you lads will try the Pachmayr Presentation grip and think carefully, I think you'll find that its oval shape much resembles an enlarged Colt grip. It's exceptionally comfortable in my hand.
I've never seen anyone mention that, but it occurred to me last year, and I think I have something there.
The basic Colt grip does fit my hands better, but aftermarket grips solve that, and Colts lose cylinder timing far faster than do S&W's, and their fixed sight guns often need the barrel turned to get the sights aligned. I've given up on Colt, but they feel good in my hands. This has been true from the Detective Special to the New Service.
If your hands do not like the same grips as mine do, I'm sorry to learn that. It's probably a genetic flaw in your family tree...(I was going to put a laughing Smilie here, but can't when I add later material. The images don't appear in Editing mode.)