I wore an ankle holster with a 2" M60 in it for ten years, and the day I discovered the DeSantis Nemesis pocket holster was the last day I ever wore an ankle holster! I went through 6 or 7 different ones, even had two custom made by the late Bruce Nelson, and his were by far the best of the bunch.
At best, even after getting used to, they are uncomfortable, difficult to access, and are always moving on your ankle unless you strap it on very tight.
After 10 years of wearing one, my personal advise would be to use a pocket holster, IWB holster, or a belt scabbard if you are able.
Just my .02 cents.
Chief38