Properly set up, the gun should wear-in, not wear-out. The best example I can give is my Model 17-5 I use in Bullseye. I had the action tuned by the Performance Center and over the years the gun has just gotten more smooth and predictable. The timing was and still is spot on. I disagree with an earlier post that the hammer should drop just after the cylinder locks. This is a very personal issue when shooting DA. Many competitors, usually those that pull straight through, want that "early" drop type action. Others, especially those that like to shoot timed and rapid DA and not SA, want what is called an "early come-up" where the cylinder locks and then there is a long-ish pull of the trigger before hammer release. I shoot mine like this and treat that final pull more or less like a single stage trigger. I don't know which is better but I do know that with an early come-up, the gun has a lot further to go before is wears to the point where the timing is late.
Keith