Just like arjay said, unscrew, using a properly fitting screwdriver, remove & replace. Remember you're just installing a thumbpiece so don't get too carried away when tightening the new one down.
Because the shape of the newer thumbpiece digs into the web of my wife's hand on her J Frames I've replaced the newer style with the older, more rounded type, on all her J's.
Since then she hasn't had any problem whatsoever.