Saw a Desantis Nemesis that will fit a CS9/CS40/CS45. Wondered if anyone has tried to pocket carry one of these?

Yes, but not with that specific holster, and only in jackets that would support the weight.

I have some very deep cargo shorts pockets that would work ... (I've tried a duty-sized pistol in those shorts and found it to disappear quite a ways below the pocket mouth) ... but it's the pressure against the front of my thigh that makes it inconvenient, for me. Just depends on the user.

FWIW, I've found my CS9 offers a less blocky outline than my G26.

The only potential issue for me has been the height and thickness of the Hogue grips.

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Ret LE Firearms inst & armorer

I can only pocket carry mine in cargo pockets but with a good pocket style holster it works well for me. I use either Recluse pocket holster or Bob Mika pocket holster.

For me, my CS-45 is too big for pocket carry. I pocket carry a 442 almost exclusively but the CS-45, if I choose to carry it, goes on a belt, IWB when I lose weight, outside belt otherwise.

***GRJ***

I carry the CS9 in the DeSantis pocket holster. Gotta have deep pockets & a wide opening for this to work. Also easier without sticky Hogue grips. I use Big Dog grips.

I carried a CS45 for a couple years as a backup in my front left uniform pocket. It worked very well, but I wear my uniform pants big and have them taken in, so it's different. I now have a CS9 and while it will fit in a pocket, it is on the big side.

While wearing cargo pants with the typical style of deep pockets, I've carried the CS9 (factory grips, flat magazine base) in the deSantis; I never really cottoned to the carry. The CS9 is more convenient in a pocket than my late unlamented Glock 26, but after all was said and done. I switched to a belt carry. Pocket carry is restricted for me to a J-Frame.