Whatever revolver you pick, get it in DA. Heavily loaded 45 Colt or 44 Mag SAs are basically going to be single shots on close-in, charging critters. That is, unless you are someone with great hand strength and demonstrated ability to fire SAs really fast and accurately on moving targets, which really means two-handed shooting.
My current carry is a 357 Mag with heavily loaded 180 grain Nosler Partition bullets at about 1100 fps. These bullets have rep of expanding to 0,4+ inches and penetrating deeply. Plus, I can draw and shoot that DA revolver quickly with these loads, especially with two handed hold.
I agree with concern about long guns. Unless you already have them in hand, they are likely to be useless on a close-in, charging critter. Also, shooter needs demonstrated ability to work lever really fast, no short stroking -- otherwise, that rifle is just a club or single shot.
Niklas