Interesting comparison. I've owned several DEs over the last 40 years and always ended up selling them after the new wore off. They're just too huge, too heavy, and too clunky to be truly practical for anything other than bragging rights, though as a younger man I certainly did go to the trouble to carry one "concealed" under a pair of athletic shorts and tank top!
It was the discovery of the .460 Rowland that finally pulled me away from all things Desert Eagle. The Rowland can be fired from a 38 ounce 1911 platform (versus 72 oz for DE), and easily matches actual factory ammo numbers between the two.
IMI isn't made up of stupid people, they know the only way to keep consumer interest in a massively huge 72 ounce pistol is to chamber it in a uniquely huge cartridge that people perceive to be so much better it's worth carrying a gigantic handgun to obtain. Fact is, anything above one Kilojoule of kinetic energy is ample to bring down every animal on the North American continent - all numbers above that are fine, but not necessary. The .460 Rowland goes 1.3-1.4 Kilojoules of energy per shot, putting right in the wheelhouse of the .44 magnum, though with almost twice as many shots, much faster reloads, and far less abusive recoil!
A 1911 chambered in .460R has far less recoil than either a .44 magnum revolver or Desert Eagle .44 magnum, and is ergonomically superior to both.
A Glock .460R with long slide weighs in at 34 ounces empty with a 6.61" barrel and steel comp, plus 6" slide that regulates the recoil of the round down to almost nothing.