Hornady lists 800X for its 125 gr XTP.
This data is pulled from load data.com as republished Hornady data. As always however, you need to obtain your own data source and verify the data rather than trusting my typing and copy/paste skills.
Notes: This data was shot by Brian Pearce, Wolfe Publishing Company. Gun: Colt Trooper 38 Special; barrel length: 4-inches; case: Starline; primer: Winchester Small Pistol; bullet diameter: .357"; maximum COAL: 1.550"; maximum case length: 1.155"; trim to length: 1.145".
125 gr Hornady HP-XTP or FP-XTP, IMR 800-X
5.6 gr, 856 fps
6.0 gr, 898 fps
6.4 gr, 951 fps
6.8 gr, 1004 fps
7.1 gr, 1052 fps
7.5 gr, 1101 fps
I use the 7.5 grain, 125 gr XTP load in my 3" Model 13, and 4" Model 19 as an "indoor" home defense load.
It expands reliably to about .480" but over penetrates to about 20"-22", so it's not ideal for self defense from a potential over penetration perspective. Still the residual velocity of an over penetrating hit isn't going to take it through an interior or exterior wall.
At standard pressure .38 Special or .38+P velocities under about 1050 fps the 125 gr XTP won't expand, so you really need a stout .38+P or .357 Magnum velocities to get good terminal performance, and a maximum load of 800X will do pretty well.
Hornady also has 800X data for its 140 and 158 gr XTP bullets, but .38+P loads don't generate enough velocity for reliable expansion (about 1000-1050 fps).
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That said, my preferred Hornady 125 gr XTP load is either 8.5 gr or 9.0 gr of Unique (depending on the revolver - I back off to 8.5 grains if the cases start sticking at 9 grains, as I like quick, clean ejection with short ejector rod 2 1/2" revolvers). Those loads give me about 1250 fps and 1300 fps in my 2 1/2" Model 66 and Model 686. At those velocities the 125 gr XTP will expand to about .530" and give me about 18" of penetration.
The 9 grain charge also makes it a light recoiling load compared to a max charge of colloidal ball powder like Win 296 or H110 and you lose little or nothing in terms of velocity a 2 1/2" barrel.