Oh, my, a debate that we should never have, but we are having it. Just my opinion....And EVERYONE will have a different opinion. So here we go....
YMMV!!
A rifle is the WORST possible choice for home defense. IMHO. A carbine is not much better except it might maneuver better in narrow hallways. If you live in a huge, palatial home, MAYBE you can use a rifle but it is not the best choice except for this:
https://media.giphy.com/media/BHfWOavrqAKuA/giphy.gif
(c) Universal Pictures,
et al
There you are, up on the second floor balcony, fighting off hordes of bad guys. If that's what you are preparing for so be it. If you are a normal person it is just silly. Even if you have baddies in the street out front as noted above you still do not need a rifle until and unless we are in the midst of an American meltdown. THEN you will need a rifle.
In the meantime, a tactical shotgun (or maybe any shotgun but the long ones will be unwieldy indoors) in any gauge and a handgun or two will be sufficient to defend your home without sending high velocity rounds over to visit all of your neighbors.
A .308 indoors? In a 16 inch gun? You better hit every home invader all at once with the first shot because that second shot is going to be hard to find! Even in semi-auto mode. I am an M-14/M1A fan, and believe me I would not ever pick that one up inside my house. I don't know who came up with the concept of using modern sporting rifles, tactical set up or just plain Jane, for home defense but they are just wrong. Home
offense is different - if you are kicking in doors and prepared to shoot terrorists, drug dealers, or other ne'er-do-wells okay, bring a long arm but you are not on TV and not para-military and your 15 round M&P/3rd Gen/SIG/Beretta/Hi-Power/six-shooter handguns will do the job, especially if backed up by a shotgun (if you can get to it).
As I said, YMMV, but I am a firm believer in not using too much gun inside your home.