The Army found that 38 long Colt out of a 5" to 6" revolver wouldn't stop a druged up attacker so they went to the 45 Colts that they had in storage, even issued some Colt new service DA revolvers in 45 colt chambers, but new Frankfort Arsenal ammo was in 45 US ( a 45 S&W length case with a 45Colt rim dia., a 230 grain lead bullet at about 830FPS). The 44Russian and Special loads at the time were 246 grains of lead at just under 800FPS, the Classic 45Colt load is 855 grains of lead at whatever speed the powder pushed it at, but around 900fps is a 7.5" SAA. And of course the Ball ACP is 230 grain JRN @ 830 FPS in a 5" 1911. In real life, Carry guns are short so you get less volicity. But big slow chunks of lead seem to end self defence problems better than small slow chunks of lead. But what do I carry? Most days a Mod-49 1 7/8", with 135 grain +P's, On some days a 3.25" 45acp auto with 230 grain Hydroshocks. Depends on my mood when I dress that day. I have a Medium frame 5 shot 44 Special Tarus, that I never carry, don't even have a belt holster for! Go with what YOU know works! Try and find some friends with lots of handguns and see if you can bring ammo and try them out. Just feeling the recoil, the weight of the guns, the group size and any sort of expantion test at say 30 feet will give you real info for compairison. It is your life you're defending, don't let me or others decide for you, do your homework and field work, spend some money on reserch, make a thought out informed decision, then practice. After about a year many people go to a second gun to cover the times the first gun was inappropriate (think back up gun). Also you will have holsters (yes with a "s") for different times, clothes, or seasons. for each gun. Try them in different positions, like every inch around the side of your waist, you'll be suprised at the comfort change an inch can make. I know it is easy for me to say but, "It's only money" Ivan