In handgun cartridge loads, even for those that end up in a carbine, it has been my experience that you NEVER need more than 18BHN, never.
All of my loads fit the firearms though. Fit is the #1 thing when it comes to shooting lead with minimal leading. Powder selection can play a part as well. Case in point: 44Mag loads that are going to be shot in a Marlin 1894. I worked on this all summer. Since I have some really nice 44 caliber moulds, take a look at this boolit:
I wanted them to shoot well out of this really cool looking rifle. Everyone knows that the Marlin 1894 in 44Mag has an oversize bore. Since this mould came in .434", I thought I was golden. Not so much!

Not to start with at least. At first I was loading on a Dillon Square Deal B. Lots of rounds in a hurry BUT, that last station acts just like a Lee Factory Crimp Die. It resized the bullet in the case. So, last gun show, I picked up a used set of 44Mag dies just for the seating/crimp die and I put them in my RL450B, no more resizing during crimp. Problem #1 solved. I was using a powder that was the lowest pressure available to make the velocity I wanted. Problem was, not enough pressure to make the bullet obturate. If they don't do that, bad things can happen!

So, straight wheel weights, air cooled over a different powder. I chose AA#9. Had lots of it, can be downloaded a bit, although I don't, uses a standard primer and puts the pressure right up to the top of the 44Mag specs. Softer bullet seals off (obturates) and is flying out of that barrel @ 1800fps, no gas checks. What kind of accuracy? Take a look for yourself. This is 100 yards and my thumb measures just over 1" tip to first knuckle, that is, when they aren't dragging!

Here:
After this group was shot, I changed the scope settings bringing it up a mite. Actually, I was super surprised that I got this kind of accuracy and had to go downrange to get a picture of it!
There is absolutely no leading with this load either. I think I need to qualify that just a bit. There was one more step that I took in this whole scenario that may have played a bit part in the results too. I took a 410ga swab and soaked it in a water based fine valve grinding compound and worked it a bit through the bore. More strokes at the chamber end than at the muzzle. This bore had a bunch of tight spots as well as machine marks.
Hope this helps.