I have an old Colt Delta that I shoot the milder stuff in and a Glock 21SF that I bought a 10mm barrel for. Some folks said that wouldn't work but I just had to find out for myself. So far, it has about 500 rounds of various factory and handloads through it, some of them very, very hot, and not a single malfunction. Accuracy is better than I get with the 45 ACP setup. This is fast becoming one of my favorites.