I have a M&P, M&Pc, and a SIG226 in 357 SIG. The 357 SIG is a fantastic performer with 125gr bullets. The M&Pc is a little flashy unless you reload for it. Unfortunately, right now this cartridge is considered boutique cartridge and is a reloading proposition, with very few exceptions. Search the thread section to find out more about it.
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I don't have Alzheimer's- My wife had me tested.